Lamar Jackson threw for 280 yards and three touchdowns to finish with a perfect passer rating as the Baltimore Ravens had little difficulty with Denver's defence in a 41-10 NFL victory.

The Ravens' Derrick Henry also surpassed a few more rushing milestones during the game in Baltimore on Sunday (Monday AEDT).

Baltimore's beleaguered defence didn't force a punt until the third quarter, but a couple of early fourth-down stops helped the Ravens (6-3) build a lead as they rebounded from last weekend's surprising loss at Cleveland.

Zay Flowers had five catches for 127 yards and two touchdowns, and Henry rushed for 107 yards and two TDs.

Rookie quarterback Bo Nix caught a touchdown pass on a trick play for Denver, but the Broncos (5-4) looked outclassed at the beginning of a tough two-game stretch on their schedule. They visit Kansas City next weekend.

Henry scored the 100th and 101st rushing touchdowns of his career, and surpassed 1000 yards on the ground on the season for the sixth time. Henry has scored in every game this season, and is the third player to manage at least 10 rushing TDs in seven consecutive years, joining LaDainian Tomlinson (2001-09) and Adrian Peterson (2007-13).

In East Rutherford, New Jersey, sensational rookie Jayden Daniels threw two touchdown passes to Terry McLaurin as Washington beat bumbling New York 27-22 for their best start to a season in almost 30 years.

Daniels hit McLaurin on scoring passes of one and 18 yards in the first half, and Austin Ekeler, filling in for the injured Brian Robinson, scored on a one-yard run as the Commanders completed a season sweep of the NFC East rival Giants (2-7).

Washington are 7-2 for the first time since 1996.

In Atlanta, Kirk Cousins threw three touchdown passes as Atlanta maintained their hold on first place in NFC South with a 27-21 victory over struggling Dallas, who took their third straight setback and lost quarterback Dak Prescott to a hamstring injury.

Cousins completed 19 of 24 passes for 222 yards, including 13 in a row at one point for the Falcons (6-3). He had scoring plays of nine yards to Drake London, 36 yards to Darnell Mooney and 11 yards to Ray-Ray McCloud, the third three-TD game of the quarterback's debut season with Atlanta.

Tyler Allgeier capped the Falcons' fifth win in six games by powering into the end zone from six yards with just over 11 minutes remaining.

The Cowboys (3-5) tried to rally behind Cooper Rush after Prescott was ruled out, having completed 18 of 24 for 133 yards and a touchdown.

In Cleveland, Justin Herbert passed for 250 yards and two touchdowns to lead the visiting Los Angeles to a 27-10 victory over the Browns.

Herbert connected on a 66-yard TD pass to Quentin Johnston and a 27-yarder to Joshua Palmer as the Chargers (5-3) built a big halftime lead and rolled to their fifth straight win over Cleveland.

In Philadelphia, the Eagles survived a second-half surge by the visiting Jacksonville Jaguars for a 28-23 victory.

Elsewhere, Nick Folk kicked a 25-yard field goal with 2:32 left in overtime as Tennessee beat the visiting New England Patriots 20-17, giving coach Brian Callahan his first victory at home this season.

In Seattle, Demarcus Robinson made a one-handed, 39-yard touchdown reception in overtime as the Los Angeles Rams stunned the Seahawks 26-20.

And in other results, Cincinnati got their first home win of the season, routing Las Vegas 41-24, Carolina snapped a five-game losing streak, beating New Orleans 23-22 in Charlotte, the Buffalo Bills beat the Miami Dolphins 30-27 in New York, and the Cardinals crushed the Chicago Bears 29-9 in Glendale, Arizona.

The Detroit Lions scored a 24-14 road win over the Las Vegas Raiders, and the Minnesota Vikings felt right at home beating the Indianapolis Colts 21-13.